Home > Medical Reference > Encyclopedia (English)

Toggle: English / Spanish

Services at Maryland General

A complete list of inpatient and outpatient healthcare services at MGH.

Neurosyphilis - Overview

Definition of Neurosyphilis:

Neurosyphilis is an infection of the brain or spinal cord. It occurs in persons with untreated syphilis many years after they are first infected.

Causes, incidence, and risk factors:

Neurosyphilis occurs about 10 to 20 years after first being infected with syphilis. It is considered a life-threatening complication of syphilis. Not everyone who has syphilis will develop this complication.

There are four different forms of neurosyphilis:

Asymptomatic neurosyphilis occurs before symptomatic syphilis. Signs of the disease may be seen in the spinal fluid, but the person has no symptoms.

Meningovascular neurosyphilis causes nerve and eye problems, among other symptoms. There may be damage to the blood vessels, which can lead to a stroke.

Persons with tabes dorsalis have damage to the spinal cord that slowly gets worse, making them unable to walk.

In general paresis, brain cell damage causes paralysis, tremors, seizures, and mental decline. Inflammation may occur anywhere in the brain or spinal cord and can lead to a number of neurological problems.

  • Reviewed last on: 3/5/2007
  • Daniel Kantor, M.D., Director of the Comprehensive MS Center, Neuroscience Institute, University of Florida Health Science Center, Jacksonville, FL. Review provided by VeriMed Healthcare Network.

References

Mandell GL, Bennett JE, Dolin R. Principles and Practice of Infectious Diseases. 6th ed. London: Churchill Livingstone; 2005:2274-2276.

U.S. Preventive Services Task Force. Screening for Syphilis Infection: Recommendation Statement. Ann Fam Med 2004; 2: 362-365.

     
Physician Directory

Physician Specialties

Medical Glossary

Guide for Patients

Guide for Visitors

    
About Us     ·     Contact Us     ·     Phone Listing     ·     Residency Programs     ·     Site Map     ·     Site Search     ·     Links     ·     FAQs

© 2008 Maryland General Hospital, All Rights Reserved   ·   827 Linden Avenue,   Baltimore, MD 21201   ·   410-225-8000
Commitment to Compliance   ·   Privacy Policy   ·   Terms and Conditions of Use   ·   Disclaimer   ·   JCAHO Public Notice