Definition of Acute cytomegalovirus (CMV) infection:

Acute cytomegalovirus (CMV) infection is a condition caused by a member of the herpesvirus family.

See also: Mononucleosis

Causes, incidence, and risk factors:

Infection with cytomegalovirus (CMV) is very common. The infection is spread by:

• Blood transfusions
• Organ transplants
• Respiratory droplets
• Saliva
• Sexual contact
• Urine

Most people are exposed to CMV in their lifetime, but typically only individuals with weakened immune systems become ill from CMV infection. Some people with this condition develop a mononucleosis-like syndrome.

In the U.S., CMV infection most commonly develops between ages 10 - 35. Most people are exposed to CMV early in life and do not realize it because they have no symptoms. People with a compromised immune system can have a more severe form of the disease.