Treatment:
Testosterone therapy may be prescribed. This can help:
Most men with this syndrome are not able to father children. However, there have been some men who have. An infertility specialist may be able to help.
Support Groups:
The American Association for Klinefelter Syndrome Information and Support (AAKSIS) - www.aaksis.orgExpectations (prognosis):
Most patients have a normal, productive life.
Complications:
The syndrome is associated with an increased risk of:
- Breast cancer
- Extragonadal germ cell tumor (a rare tumor)
- Lung disease
- Varicose veins
- Osteoporosis
- Autoimmune disorders such as lupus, rheumatoid arthritis, and Sjogren syndrome
- Learning disabilities, despite normal or high IQ
- Dyslexia
- Attention deficient hyperactivity disorder
- Depression
Taurodontism, which is when the teeth have enlarged pulp and a thinning surface, is very common in Klinefelter syndrome. It can be diagnosed by dental x-rays.
Calling your health care provider:
Call for an appointment with your health care provider if a boy does not develop secondary sexual characteristics at puberty. A genetics counselor can help explain abnormal chromosome findings. A consultation with an endocrinologist and infertility specialist may also be helpful.
