Alternative Names
Primary sclerosing cholangitis
Definition of Sclerosing cholangitis:
Sclerosing cholangitis is swelling (inflammation) of the bile ducts of the liver without a known cause.
Causes, incidence, and risk factors:
In this condition, the bile ducts inside and outside the liver become narrowed and scarred. The cause is unknown.
The disease is associated with inflammatory bowel disease (Crohn's disease and ulcerative colitis), and genetic factors may also be responsible. Sclerosing cholangitis occurs more often in men than women. This disorder is rare in children.