Flucytosine (By mouth)

Introduction:

Flucytosine (floo-SYE-toe-seen)

Treats serious fungal infections.

Brand Name(s):

Ancobon

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to flucytosine.

How to Use This Medicine:

Tablet, Capsule

  • Your doctor will tell you how much medicine to take and how often.
  • Keep taking the medicine for as long as your doctor has ordered, even if you feel better. If you stop taking the medicine too soon, your infection may not completely go away.
  • This medicine may upset your stomach. If you take more than one capsule for each dose, wait a few minutes after taking the first capsule before you take the next one. This may help reduce nausea or stomach upset.

If a dose is missed:

  • Take the missed dose as soon as possible, unless it is almost time for your next dose.
  • Skip the missed dose if it is almost time for your next regular dose.
  • You should not use two doses at the same time.

How to Store and Dispose of This Medicine:

  • Store the medicine at room temperature, away from heat, direct light, and moisture.
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also taking cytarabine (Cytosar®).

Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
  • Before you take flucytosine, make sure your doctor knows if you have kidney, liver, bone marrow, or blood disease or if you have been given anti-cancer drugs or radiation treatment.
  • This medicine may make your skin more sensitive to sunlight and cause a rash or sunburn. Avoid being in the sun for long periods. Protect your skin with sunscreen and clothing when you are outside.
  • If this medicine makes you dizzy or drowsy, avoid driving or using machinery.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Unusual bruising or bleeding
  • Unexplained fever or sore throat
  • Rash or hives
  • Trouble breathing
  • Yellowing of your skin or eyes
  • Bloody urine or urinating less than one cup in a day
  • Chest pain

If you notice these less serious side effects, talk with your doctor:

  • Upset stomach, nausea, vomiting
  • Headache
  • Dizziness or drowsiness
  • Mild diarrhea
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